Form: Lyophilized powder
Purity: >99%
IGF1-LR3 is a synthetic human growth factor that enhances cellular growth, muscle repair, and fat metabolism, all of which are essential for high-level research. This peptide is highly pure and has versatile applications that give in-depth and new insights into the processes of growth, repair, and metabolism.
IGF1-LR3 1MG
IGF-1 LR3 is a 83-amino-acid analog of insulin-like growth factor 1 engineered by extending the native 70-residue sequence with a 13-residue N-terminal peptide, replacing the third amino acid with arginine.
These changes reduce its affinity IGF-binding proteins and protect it from rapid enzymatic cleavage, prolonging plasma half-life from ~10 min to 6–10 h. Freed from most carrier constraints, IGF-1 LR3 more readily engages IGF-1 receptors (and, to a lesser extent, insulin receptors), triggering the canonical PI3K-Akt-mTOR and MAPK/ERK pathways that drive glucose uptake, protein synthesis, mitosis, and tissue remodeling.
